Monday, May 14, 2012

Contagion

 Released Year: 2011
Directed by Steven Soderbergh

Casted by
Matt Damon as Mitch Emhoff
Marion Cotillard as Dr. Leonora Orantes
Laurence Fishburne as Dr. Ellis Cheever
Kate Winslet as Dr. Erin Mears
Jude Law as Alan Krumwiede
Gwyneth Paltrow as Elizabeth "Beth" Emhoff
 Story:
 The film follows several interacting plotlines, with no single protagonist nor antagonist, over the course of several weeks from the initial outbreak and attempts to contain it, to panic and decay of social order, and, finally, to the introduction of a vaccine. It is revealed in the end of the movie how the virus began.

After a business trip to Hong Kong, businesswoman Beth Emhoff stops in Chicago for a dalliance with an old boyfriend before returning to her husband and family in suburban Minneapolis. At first she appears to have contracted a cold during her trip. Her son, Clark, also becomes symptomatic and is sent home from school. Beth's condition worsens and two days later she collapses with severe seizures in her home. Beth's husband, Mitch, rushes her to the hospital, but she continues to seize and dies of an unknown virus. Because it affects the brain and central nervous system, pathologists attribute it to a meningoencephalitis virus. Mitch returns home and finds that Clark has also died from a similar infection. Mitch is put in isolation but turns out to be genetically immune to the disease. He and his daughter attempt to flee the city, but a military quarantine has been imposed, and they are forced to return to their home to face decaying social order and rampant looting of stores and homes. Not knowing whether his daughter inherited his immunity, Mitch struggles to balance his teenage daughter's frustration with quarantine with his desire to protect her, while trying to come to terms with his own loss.

In Atlanta, representatives from the Department of Homeland Security meet with Dr. Ellis Cheever of the Centers for Disease Control and Prevention and express fears that the disease is a bioweapon intended to cause terror over the Thanksgiving weekend. Cheever sends Dr. Erin Mears, an Epidemic Intelligence Service officer, to Minneapolis to begin the investigation. In addition to tracing the outbreak back to Beth, Dr. Mears has to negotiate with local bureaucrats reluctant to commit resources. She later becomes infected with the disease after being in contact with contaminated fomites while staying at her hotel. The Minnesota National Guard arrives to quarantine the city, and a badly deteriorating Dr. Mears is moved to the field medical station she helped set up, where she later dies.

Investigations into cures via treatment protocols or vaccines initially prove fruitless as scientists cannot find a culture to grow the new virus, which has been named the Meningoencephalitis Virus One (MEV-1). Professor Ian Sussman violates orders from a CDC scientist, Dr. Ally Hextall, to destroy his samples and identifies a line of bat cells that will support research of a vaccine. At the CDC, Dr. Hextall uses this breakthrough to begin to characterize the properties of the virus, which turns out to have a mix of genetic material from bat, pig and human viruses and appears to spread via fomites with a basic reproduction number of two. This later goes up to four after the virus mutates.

A conspiratorially minded freelance internet blogger, Alan Krumwiede, posts videos about the disease, and in one of them appears sick and later claims that he recovered using a homeopathic cure called forsythia. Panicked people attempting to obtain forsythia overwhelm pharmacies, accelerating the contagion as infected and healthy people congregate. Krumwiede leaps to national attention and, during a television interview, accuses Dr. Cheever of informing friends and family to leave Chicago before a quarantine is imposed. It is later revealed Krumwiede was never sick with the virus, but was attempting to boost demand on behalf of investors in the companies producing and distributing the homeopathic treatment. He is arrested for conspiracy and fraud, but is soon released after his 12 million blog readers collect and pay his bail.

Dr. Hextall identifies a potential vaccine, using an attenuated (live) virus. Because of the difficulties of human subjects testing, she follows the precedent of other vaccine researchers and inoculates herself first. Hextall visits her gravely ill father in the hospital to expose herself to the virus and test the vaccine. Production of the vaccine is rapidly ramped up and the CDC awards vaccinations via a random lottery based on birth dates for one full year until every survivor is vaccinated. Dr. Cheever, feeling guilty for his past actions to protect those who are close to him, gives his fast-tracked MEV-1 vaccination to the son of a janitor he works with at the disease center. Dr. Hextall places the surviving samples of the MEV-1 virus in cryogenic storage with H1N1 and SARS.

Dr. Leonora Orantes, a World Health Organization epidemiologist, travels to Hong Kong to trace the origins of the infections. She collaborates with Sun Feng and other local Chinese epidemiologists and public health officials and they identify Emhoff as patient zero. As the virus spreads, Feng kidnaps Orantes to use her as leverage to obtain the first MEV-1 vaccines for his village. Orantes spends months living in rural China with the villagers until the vaccine is announced. Feng exchanges Orantes for the vaccines, which turn out to be placebos. Orantes rushes away when she is informed of this, presumably to warn the village.

The film concludes by tracing the origin of the virus from a bat nesting in a tree being cleared by Emhoff's mining corporation. The bat flies to a nearby pig sty and drops a banana where it is eaten by the pig, presumably transferring the bat virus into the pig. The pig is sold to and butchered by a chef in a Macau casino, who greets Beth Emhoff without washing his hands of the pig's blood, transferring the bat-pig hybrid to her and creating the MEV-1 human strain.
L² Scored: 10/10

L² Comment:
Oh fuck, this is an extremely good film. I love all those big casts and the storyline, there's almost flawless in this film~ excellent work and excellent cast :)

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